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Invitrogen™ SFTPC Monoclonal Antibody (5E6A9)
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Product Code. 15358130
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Quantity:
100 μg
Unit Size:
100µg
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15358130 100 μg 100µg
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Product Code. 15358130 Supplier Invitrogen™ Supplier No. MA517172

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Description

Mouse Monoclonal Antibody

MA5-17172 targets SFTPC in indirect ELISA and WB applications and shows reactivity with Human samples. The MA5-17172 immunogen is purified recombinant fragment of human SFTPC (amino acids: 60-180 ) expressed in E. Coli. MA5-17172 detects SFTPC which has a predicted molecular weight of approximately 21kDa.

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SFTPC
Applications ELISA, Western Blot
Classification Monoclonal
Clone 5E6A9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Sftpc
Gene Accession No. P11686
Gene Alias BRICD6; BRICHOS domain containing 6; LOW QUALITY PROTEIN: pulmonary surfactant-associated protein C; pro-SpC; PSP C; PSP-C; pulmonary surfactant apoprotein-2 SP-C; pulmonary surfactant associated protein C; pulmonary surfactant protein C; pulmonary surfactant-associated protein C; Pulmonary surfactant-associated proteolipid SPL(Val); SFTP 2; SFTP2; Sftp-2; Sftpc; SMDP2; SP C; SP5; SPC; SP-C; surfactant associated protein C; surfactant protein C; Surfactant pulmonary-associated protein C; Surfactant, pulmonary-associated protein C; surfactant-associated protein; type I SP-C; type I surfactant protein C; type II SP-C; type II surfactant protein C
Gene Symbols Sftpc
Host Species Mouse
Immunogen Purified recombinant fragment of human SFTPC (amino acids: 60-180 ) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6440
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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