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SGI-1027, MedChemExpress

Product Code. 16445938
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50 mg
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Description

MedChemExpress SGI-1027 is a DNA methyltransferase (DNMT) inhibitor, with IC50s of 7.5 μM, 8 μM, and 12.5 μM for DNMT3B, DNMT3A, and DNMT1 with poly(dI-dC) as substrate.

SGI-1027 is a DNA methyltransferase (DNMT) inhibitor, with IC50s of 7.5 μM, 8 μM, and 12.5 μM for DNMT3B, DNMT3A, and DNMT1 with poly(dI-dC) as substrate.

Specifications

Chemical Name or Material SGI-1027
CAS 1020149-73-8
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C27H23N7O
Quantity 10 mg
Solubility Information DMSO : 27 mg/mL (58.50 mM; Need ultrasonic and warming)
SMILES O=C(NC1=CC=C(NC2=NC(N)=NC(C)=C2)C=C1)C3=CC=C(NC4=CC=NC5=CC=CC=C45)C=C3
Molecular Weight (g/mol) 461.52
Formula Weight 461.52
Percent Purity 99.35%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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