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Invitrogen™ SGK1 Recombinant Rabbit Monoclonal Antibody (3P4N3)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA535420
This item is not returnable.
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Description
Immunogen sequence: MTVKTEAAKG TLTYSRMRGM VAILIAFMKQ RRMGLNDFIQ KIANNSYACK HPEVQSILKI SQPQEPELMN ANPSPPPSPS QQINLGPSSN PHAKPSDFHF.
SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
Specifications
| SGK1 | |
| Recombinant Monoclonal | |
| 1.06 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O00141, Q9WVC6 | |
| SGK1 | |
| A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SGK1 (O00141). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 3P4N3 | |
| Unconjugated | |
| SGK1 | |
| serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; serum/glucocorticoid regulated kinase 1; serum/glucocorticoid-regulated kinase 1; Sgk; SGK1; Sgk1 variant i3 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 20393, 6446 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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