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Invitrogen™ SGSM1 Polyclonal Antibody
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Product Code. 15759990 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15759990 100 μL 100µL
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Product Code. 15759990 Supplier Invitrogen™ Supplier No. PA552038

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SPDSGHPSSH NFSSGLSEHS EPSLSTEDSV LDAQRNTPTV LRPRDGSVDD RQSSEATTSQ DEAPREELAV QDSLESDLLA NESMDEFMSI TGSLDMALPE KDDVVMEGWR SSETEKHGQA DSEDNLSEEP EMESLFPALA SLAVTT Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.

Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1, 148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SGSM1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SGSM1
Gene Accession No. Q2NKQ1
Gene Alias 2410098H20Rik; AA408781; D5Bwg1524e; E130107M15; KIAA1941; NuIP; nurr1-interacting protein; RUN and TBC1 domain containing 2; RUN and TBC1 domain-containing protein 2; RUTBC2; SGSM1; Small G protein signaling modulator 1; small G protein signaling modulator 1 protein
Gene Symbols SGSM1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SGSM1. Recombinant protein control fragment (Product #RP-91520).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 129049
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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