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Invitrogen™ SHANK1 Monoclonal Antibody (M369)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA547733
This item is not returnable.
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Description
This antibody detects a 225 kDa* protein corresponding to the molecular mass of Shank1 on SDS-PAGE immunoblots of adult mouse brain.
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
Specifications
| SHANK1 | |
| Monoclonal | |
| 0.25 mg/mL | |
| PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide | |
| D3YZU1, Q9WV48, Q9Y566 | |
| SHANK1 | |
| Clone M369 was generated from a sequence corresponding to amino acids in the C-terminal region of rat Shank1. This sequence has high homology to human and mouse Shank1. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Western Blot | |
| M369 | |
| Unconjugated | |
| SHANK1 | |
| GKAP/SAPAP interacting protein; GKAP/SAPAP-interacting protein; OTTHUMP00000174437; SAPAP-interacting protein synamon; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains protein 1; SH3/ankyrin domain gene 1; SHANK 1; Shank1; Shank1a; somatostatin receptor-interacting protein; SPANK 1; Spank1; SPANK-1; SSTR-interacting protein; Sstrip; Synamon | |
| Mouse | |
| Protein A | |
| RUO | |
| 243961, 50944, 78957 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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