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Invitrogen™ SHMT1 Monoclonal Antibody (K56009_4G3), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA556123
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Description
Sequence of this protein is as follows: MTMPVNGAHK DADLWSSHDK MLAQPLKDSD VEVYNIIKKE SNRQRVGLEL IASENFASRA VLEALGSCLN NKYSEGYPGQ RYYGGTEFID ELETLCQKRA LQAYKLDPQC WGVNVQPYSG SPANFAVYTA LVEPHGRIMG LDLPDGGHLT HGFMTDKKKI SATSIFFESM PYKVNPDTGY INYDQLEENA RLFHPKLIIA GTSCYSRNLE YARLRKIADE NGAYLMADMA HISGLVAAGV VPSPFEHCHV VTTTTHKTLR GCRAGMIFYR KGVKSVDPKT GKEILYNLES LINSAVFPGL QGGPHNHAIA GVAVALKQAM TLEFKVYQHQ VVANCRALSE ALTELGYKIV TGGSDNHLIL VDLRSKGTDG GRAEKVLEAC SIACNKNTCP GDRSALRPSG LRLGTPALTS RGLLEKDFQK VAHFIHRGIE LTLQIQSDTG VRATLKEFKE RLAGDKYQAA VQALREEVES FASLFPLPGL PDF
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
Specifications
| SHMT1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.09% sodium azide | |
| P34896 | |
| Shmt1 | |
| Recombinant human SHMT1 (immunogen range is 1-483). | |
| 200 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| K56009_4G3 | |
| Unconjugated | |
| Shmt1 | |
| AI324848; AI385541; C81125; CSHMT; cytoplasmic serine hydroxymethyltransferase; cytosolic form; cytosolic serine hydroxymethyltransferase; glycine hydroxymethyltransferase; LRRGT00032; MEL-32; MGC15229; MGC24556; mshmt; mshmt1; mshmt2; serine hydroxymethyl transferase; serine hydroxymethyltransferase; serine hydroxymethyltransferase 1; serine hydroxymethyltransferase 1 (soluble); serine hydroxymethyltransferase 1 (soluble) isoform 1; serine hydroxymethyltransferase 2 (mitochondrial); serine hydroxymethyltransferase, cytosolic; Serine methylase; SHMT; Shmt1; shmt1 protein; SHMT2; zgc:66171; zgc:77524; zSHMT-1 | |
| Mouse | |
| Protein A | |
| RUO | |
| 6470 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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