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Invitrogen™ SIAH1 Polyclonal Antibody
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Product Code. 16518981
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Quantity:
100 μL
Unit Size:
100µL
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16518981 100 μL 100µL
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Product Code. 16518981 Supplier Invitrogen™ Supplier No. PA596137

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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse kidney; Cellular Location: Cytoplasm, Nucleus Immunogen sequence: MTGKATPPSL YSWRGVLFTC LPAARTRKRK EMSRQTATAL PTGTSKCPPS QRVPALTGTT ASNNDLASLF ECPVCFDYVL PPILQCQSGH LVCSNCRPKL TCCPTCRGPL GSIRNLAMEK VANSVLFPCK YASSGCEITL PHTEKADHEE LCEFRPYSCP CPGASCKWQG SLDAVMPHLM HQHKSITTLQ GEDIVFLATD INLPGAVDWV MMQSCFGFHF MLVLEKQEKY DGHQQFFAIV QLIGTRKQAE NFAYRLELNG HRRRLTWEAT PRSIHEGIAT AIMNSDCLVF DTSIAQLFAE NGNLGINVTI SMC.

This gene encodes a protein that is a member of the seven in absentia homolog family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIAH1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.03 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SIAH1
Gene Accession No. P61092, Q06985, Q8IUQ4, Q920M9
Gene Alias AA960570; AA982064; AI853500; E3 ubiquitin-protein ligase SIAH1; E3 ubiquitin-protein ligase SIAH1A; E3 ubiquitin-protein ligase SIAH1B; FLJ08065; h HUMSIAH; hSIAH1; HUMSIAH; mSiah-1a; RING-type E3 ubiquitin transferase SIAH1; RING-type E3 ubiquitin transferase SIAH1A; RING-type E3 ubiquitin transferase SIAH1B; seven in absentia 1A; seven in absentia 1B; seven in absentia homolog 1; Seven in absentia homolog 1a; Seven in absentia homolog 1b; SIAH; siah E3 ubiquitin protein ligase 1; SIAH1; siah-1; Siah1a; Siah-1a; Siah1b; siah-1b; Sinh1a; Sinh1b
Gene Symbols SIAH1, Siah1a, Siah1b
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human SIAH1 (NP_0010066111).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110337437, 140941, 20437, 20438, 6477
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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