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SIGLEC9 Mouse anti-Human, Clone: OTI3G8, liquid, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies TA500373
This item is not returnable.
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Description
Siglec9 (Sialic acid-binding Ig-like lectin 9) is single-pass type I membrane protein and belongs to immunoglobulin super family and contains two Ig-like C2 type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is reported that Siglec9 recognizes sialic acid in alpha2, 3-or alpha2, 6-glycosidic linkage to galactose. Using a specific antibody, Siglec9 was found to be expressed at high or intermediate levels by monocytes, neutrophils, and a minor population of CD16+, CD56- cells. Siglec9 also acts as an inhibitory receptor for MUC16 that attenuates T- andNK cell function. Recent reports suggest that Siglec9 expressed on DCs is involved in immuno regulation through ligation with mucins in an epithelial cancer patient.Specifications
| SIGLEC9 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q9Y336 | |
| SIGLEC9 | |
| Full-length protein expressed in 293T cell transfected with human SIGLEC9 expression vector | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI3G8 | |
| Unconjugated | |
| SIGLEC9 | |
| CD329, CDw329, FOAP-9, OBBP-LIKE, siglec-9 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 27180 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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