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Invitrogen™ Human sIL-6ST/gp130/CD130 ELISA Kit

Product Code. 17727963
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Quantity:
10 x 96 Tests
Unit Size:
Pack of 10
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Product Code. 17727963

Brand: Invitrogen™ EHIL6STX10

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Description

ELISA

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P40189
Assay Range 8.23 to 6000 pg/mL
Assay Sensitivity 4 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 3572
Gene Symbol IL6ST
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 10 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 1 μL, Serum 1 μL, Supernatant 100 μL
Storage Requirements 2°C to 8°C
Target GP130
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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