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Invitrogen™ SIM2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA568975
This item is not returnable.
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Description
This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Specifications
| SIM2 | |
| Polyclonal | |
| Unconjugated | |
| SIM2 | |
| BHLHE15; Class E basic helix-loop-helix protein 15; HMC13F06; HMC29C01; mSIM; SIM; SIM bHLH transcription factor 2; SIM transcription factor; sim2; single-minded 2; single-minded family bHLH transcription factor 2; single-minded homolog 2; single-minded homolog 2 (Drosophila); single-minded protein; transcription factor SIM2 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 6493 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| Q14190 | |
| SIM2 | |
| synthetic peptide directed towards the N terminal region of human SIM2. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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