missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ SIN3A Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA590691
This item is not returnable.
View return policy
Description
Positive Samples: HeLa, COS7, U-937, MCF-7, 293T, Mouse spleen; Cellular Location: Nucleus, nucleolus Immunogen sequence: MKRRLDDQES PVYAAQQRRI PGSTEAFPHQ HRVLAPAPPV YEAVSETMQS ATGIQYSVTP SYQVSAMPQS SGSHGPAIAA VHSSHHHPTA VQPHGGQVVQ SHAHPAPPVA PVQGQQQFQR.
Mammalian Sin3 (mSin3) is a 150 kDa protein closely related to the yeast SIN3 repressor protein involved in the transcriptional repression of many genes. There are two mammalian isoforms, mSin3A and mSin3B. Containing 4 paired amphipathic helix domains (PAH domains), mSin3A and mSin3B have been shown to directly interact with several other transcriptional repressor proteins including HDAC1, HDAC2, RbAp46, the methyl CpG binding protein MeCP2, the Mad/Max heterodimer, and the corepressors silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR).
Specifications
| SIN3A | |
| Polyclonal | |
| Unconjugated | |
| SIN3A | |
| AW553200; Histone deacetylase complex subunit Sin3a; Kiaa4126; Mammalian Sin3A; mKIAA4126; mSin3A; Paired amphipathic helix protein Sin3a; SIN; Sin3; SIN3 homolog A, transcription regulator; SIN3 transcription regulator family member A; SIN3 transcription regulator homolog A; SIN3A; transcriptional corepressor Sin3a; transcriptional co-repressor Sin3A; transcriptional regulator, SIN3 yeast homolog A; transcriptional regulator, SIN3A; transcriptional regulator, SIN3A (yeast) | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 20466, 25942, 363067 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 0.51 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
| Q60520, Q96ST3 | |
| SIN3A | |
| Synthetic peptide. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction