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Invitrogen™ SIN3B Polyclonal Antibody
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Product Code. 13445217
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
13445217 100 μL 100µL
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Product Code. 13445217 Supplier Invitrogen™ Supplier No. PA530707

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2, HCT116, mouse brain. Predicted reactivity: Mouse (92%), Rat (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIN3B
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.57 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene SIN3B
Gene Accession No. O75182, Q62141
Gene Alias 2810430C10Rik; Histone deacetylase complex subunit Sin3b; KIAA0700; Paired amphipathic helix protein Sin3b; SIN3 homolog B, transcription regulator; SIN3 homolog B, transcriptional regulator; SIN3 transcription regulator family member B; SIN3 transcription regulator homolog B; SIN3B; Transcriptional corepressor Sin3b; transcriptional regulator, SIN3 yeast homolog B; transcriptional regulator, SIN3B; transcriptional regulator, SIN3B (yeast)
Gene Symbols SIN3B
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SIN3B. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20467, 23309
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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