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Invitrogen™ SIPA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ PA588447

Product Code. 16556691

€ 520.00 / 100µL

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Description

Immunogen sequence: ESGRPRRSFS ELYTLSLQEP SRRGAPDPVQ DEVQGVTLLP TTKQLLHLCL QDGGSPPGPG DLAEERTEFL HSQNSLSPRS SLSDEAPVLP NTTPDLLLAT TAKPSVPSAD SETPLTQDRP GSPSGSEDKG NPAPELRASF LPRTLSLRNS ISRIMSEAGS GTLEDEWQAI SEIASTCNTI LESLSREGQP IPESGDPKGT PKSDAEPEPG NLSEKVSHLE SMLRKLQEDL QKEKADRAAL EEEVRSLRHN NRRLQAESES AATRLLLASK QLGSPTADLA; Positive Samples: Raji, K-562, HeLa, LO2, Mouse spleen; Cellular Location: Cytoplasm, Endomembrane system, Nucleus, Peripheral membrane protein, perinuclear region.

The product of this gene is a mitogen induced GTPase activating protein. It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

Specifications

Antigen	SIPA1
Classification	Polyclonal
Conjugate	Unconjugated
Gene	SIPA1
Gene Alias	GTPase-activating protein Spa-1; MGC102688; MGC17037; p130 SPA-1; signal-induced proliferation associated gene 1; signal-induced proliferation-associated 1; signal-induced proliferation-associated gene 1; signal-induced proliferation-associated protein 1; SIPA1; Sipa-1; SPA1
Host Species	Rabbit
Purification Method	Affinity chromatography
Regulatory Status	RUO
Gene ID (Entrez)	20469, 6494
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	ELISA, Western Blot
Concentration	0.53 mg/mL
Formulation	PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.	P46062, Q96FS4
Gene Symbols	SIPA1
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 763-1042 of human SIPA1 (NP_69498529).
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human, Mouse
Product Type	Antibody
Isotype	IgG

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Invitrogen™ SIPA1 Polyclonal Antibody

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