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SIRT5 Monoclonal Antibody (OTI2C4), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA503233
This item is not returnable.
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Description
SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.Specifications
| SIRT5 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q9NXA8 | |
| SIRT5 | |
| Full length human recombit protein of human SIRT5 produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot | |
| OTI2C4 | |
| Unconjugated | |
| SIRT5 | |
| SIR2L5 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 23408 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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