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Invitrogen™ SLC11A1 Monoclonal Antibody (910825)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561949
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Specifications
| SLC11A1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| P49279 | |
| SLC11A1 | |
| NS0 mouse myeloma cell line transfected with human NRAMP1/SLC11A1, Met1-Gly550. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Flow Cytometry, Western Blot | |
| 910825 | |
| Unconjugated | |
| SLC11A1 | |
| Bcg; host resistance locus Bcg/Ity/Lsh; integral membrane protein; Itg; Ity; Lsh; natural resistance associated macrophage protein; natural resistance associated macrophage protein 1; natural resistance-associated macrophage protein; natural resistance-associated macrophage protein 1; natural resistance-associated macrophages protein 1; NRAMP; NRAMP 1; Nramp1; Slc11a1; solute carrier 11 family member 1; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1; solute carrier family 11 (sodium/phosphate symporters), member 1; solute carrier family 11 A1; solute carrier family 11 member 1; solute carrier family 11 member a1 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 6556 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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