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Invitrogen™ SLC2A13 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA552311
This item is not returnable.
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Description
Immunogen sequence: ITFKPIAPSG QNATCTRYSY CNECMLDPDC GFCYKMNKST VIDSSCVPVN KASTNEAAWG RCENETKFKT EDI Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 88%.
SLC2A13 (solute carrier family 2 (facilitated glucose transporter), member 13) is a 648 multi-pass membrane protein that belongs to the major facilitator superfamily and the sugar transporter family. SLC2A13 is a H+-myo-inositol cotransporter that can also transport related stereoisomers. Human SLC2A13 shares 90% identity with its rat homolog. The rat sequence has 12 transmembrane domains, 3 N-glycosylation sites, several motifs important for glucose transport activity, and an endoplasmic reticulum retention signal and dileucine internalization signal in the N-terminal region. SLC2A13 has been shown to specifically transport myoinositol but not hexoses, and decreasing the pH of the extracellular medium from 7.0 to 5.0 markedly increased transport activity.
Specifications
| SLC2A13 | |
| Polyclonal | |
| Unconjugated | |
| SLC2A13 | |
| 6530403A04; A630029G22Rik; AI505012; Gm308; h(+)-myo-inositol cotransporter; H(+)-myo-inositol symporter; Hmit; proton (H+) myo-inositol symporter; proton myo-inositol cotransporter; proton myo-inositol symporter; SLC2A13; solute carrier family 2 (facilitated glucose transporter), member 13; solute carrier family 2 member 13 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 114134 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.3 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q96QE2 | |
| SLC2A13 | |
| Recombinant protein corresponding to Human SLC2A13. Recombinant protein control fragment (Product #RP-88658). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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