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Invitrogen™ SLC39A3 Polyclonal Antibody
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Product Code. 15771352 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15771352 100 μL 100µL
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Product Code. 15771352 Supplier Invitrogen™ Supplier No. PA563582

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LPVKIIETDF EKAHRSKKIL S Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 86%.

The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC39A3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLC39A3
Gene Accession No. Q9BRY0
Gene Alias AI845814; SLC39A3; solute carrier family 39 (zinc transporter), member 3; solute carrier family 39 member 3; Zinc transporter ZIP3; Zip3; ZIP-3; Zrt- and Irt-like protein 3
Gene Symbols SLC39A3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SLC39A3. Recombinant protein control fragment (Product #RP-104521).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29985
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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