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Invitrogen™ SLC5A5 Monoclonal Antibody (14F), FITC
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA545490
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Description
1 μg/mL of MA5-45490 was sufficient for detection of hNIS in 20 μg of transfected COS-7 cell membrane lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 97kDa, non-glycosylated version at 68kDa. Other minor bands associated with hNIS at 160kDa, and degradation products at approximately 30 kDa, and approximately 15kDa.
Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.
Specifications
| SLC5A5 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS, 9.1mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4 | |
| Q63008, Q92911, Q99PN0 | |
| SLC5A5 | |
| Mannose binding protein hNIS fusion (AA468-643). | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (PFA fixed), Western Blot, Microarray | |
| 14F | |
| FITC | |
| SLC5A5 | |
| Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na(+)/I(-)-symporter; Na+/I- symporter; Nis; SLC5A5; sodium iodide symporter; Sodium/iodide cotransporter; sodium-iodide symporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; solute carrier family 5 member 5; solute carrier family 5, member 5; TDH1 | |
| Mouse | |
| Protein G | |
| RUO | |
| 114479, 114613, 6528 | |
| 4°C, store in dark | |
| Liquid |
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