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Invitrogen™ SLC8A1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5104159
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Description
Antibody detects endogenous levels of total SLC8A1.
Ca2+ plays a critical role in intracellular signaling and thus regulation of calcium balance is critical for the maintenance of this signaling function. The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types. NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. In mammals, at least 5 distinct genes code for the exchangers: Three NaCX (NaCX-1, NaCX-2, and NaCX-3), and two in the NaCKX family (NaCKX-1 and NaCKX-2). NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling (Matsuoka et al., 1993). NACX-1 may also be a target for protection of the heart and brain from ischemia and reperfusion injury (Hagihara et al., 2005; Bano et al., 2005; Choi, 2005).
Specifications
| SLC8A1 | |
| Polyclonal | |
| Unconjugated | |
| Slc8a1 | |
| AI852629; AV344025; CNC; D930008O12Rik; Na(+)/Ca(2+)-exchange protein 1; Na/Ca exchanger; Na+/Ca++ exchanger; Na+/Ca2+ exchanger; Na-Ca exchanger; Ncx; Ncx1; Slc8a1; Sodium/calcium exchanger 1; sodium/calcium exchanger isoform NaCa7; solute carrier family 8 (sodium/calcium exchanger), member 1; solute carrier family 8 member 1; solute carrier family 8 member A1; solute carrier family 8, member 1 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 20541, 29715, 6546 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P32418, P70414, Q01728 | |
| Slc8a1 | |
| A synthesized peptide derived from human SLC8A1(Accession P32418), corresponding to amino acid residues Y261-E311. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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