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Invitrogen™ SMAD6 Monoclonal Antibody (5H3)

Description
MA5-15687 targets SMAD6 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15687 immunogen is purified recombinant fragment of human SMAD6 expressed in E. Coli. . MA5-15687 detects SMAD6 which has a predicted molecular weight of approximately 53kDa.
SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
Specifications
Specifications
| Antigen | SMAD6 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 5H3 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | ascites with 0.03% sodium azide |
| Gene | SMAD6 |
| Gene Accession No. | O43541 |
| Gene Alias | AOVD2; b2b390Clo; HsT17432; MAD homolog 6; mad homolog 7; Madh6; Madh7; Mothers against decapentaplegic homolog 6; mothers against decapentaplegic, drosophila, homolog of, 6; mothers against DPP homolog 6; Msmad6; SMAD; SMAD 6; SMAD family member 6; SMAD SMAD; SMAD, mothers against DPP homolog 6; SMAD6 |
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