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Invitrogen™ SMAD6 Polyclonal Antibody

Description
Immunogen sequence: PRPMSEPGAG AGSSLLDVAE PGGPGWLPES DCETVTCCLF Highest antigen sequence indentity to the following orthologs: Mouse - 90%, Rat - 90%.
SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
Specifications
Specifications
| Antigen | SMAD6 |
| Applications | Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.05 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | SMAD6 |
| Gene Accession No. | O43541 |
| Gene Alias | AOVD2; b2b390Clo; HsT17432; MAD homolog 6; mad homolog 7; Madh6; Madh7; Mothers against decapentaplegic homolog 6; mothers against decapentaplegic, drosophila, homolog of, 6; mothers against DPP homolog 6; Msmad6; SMAD; SMAD 6; SMAD family member 6; SMAD SMAD; SMAD, mothers against DPP homolog 6; SMAD6 |
| Gene Symbols | SMAD6 |
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Product Title
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