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SMC1A Mouse anti-Human, Mouse, Clone: OTI11E1, lyophilized, TrueMAB™

Product Code. 17600752
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Quantity:
100 μg
Unit Size:
100µg
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17600752 100 μg 100µg
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Product Code. 17600752 Supplier Origene Technologies Supplier No. CF809790

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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Structural Maintece of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregatior defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.

Specifications

Antigen SMC1A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI11E1
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene SMC1A
Gene Accession No. Q14683, Q9CU62
Gene Alias CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB
Gene Symbols Smc1a
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 889-1016 of human SMC1A produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24061, 8243
Target Species Human, Mouse
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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