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Invitrogen™ SMPD3 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5143767

Product Code. 17846768

  • € 536.00 / 100µL

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Description

Description

The antibody detects a 78 kDa* band corresponding to nSMase2 on SDS-PAGE immunoblots of adult mouse brain and rat PC12 cells.

Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SMPD3
Polyclonal
Unconjugated
SMPD3
4631433G07Rik; AI427456; AW537966; Cca1; confluent 3Y1 cell-associated 1; confluent 3Y1 cell-associated protein 1; fro; neutral sphingomyelin phosphodiesterase 3; neutral sphingomyelinase 2; Neutral sphingomyelinase II; NSMASE2; nSMase-2; SMPD3; Sphingomyelin phosphodiesterase 3; sphingomyelin phosphodiesterase 3, neutral; sphingomyelin phosphodiesterase 3, neutral membrane; sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
Rabbit
Antigen affinity chromatography
RUO
55512, 58994, 94338
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot, Immunocytochemistry
0.5 mg/mL
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
O35049, Q9JJY3, Q9NY59
SMPD3
nSMase2 synthetic peptide corresponds to amino acids in the C-terminal region of human nSMase2. This sequence is highly conserved in rat and mouse nSMase2, and has low homology to other nSMase family members.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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