missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Pyridines and derivatives
  7. Sorafenib Tosylate, MedChemExpress

Sorafenib Tosylate, MedChemExpress

Product Code. 16434766
Encompass_Preferred
Click to view available options
Quantity:
100 mg
500 mg
Unit Size:
100mg
500mg
This item is not returnable. View return policy

Product Code. 16434766

Brand: Medchem Express HY10201A

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress Sorafenib Tosylate (Bay 43-9006 Tosylate) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively.

SorafenibTosylate is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib Tosylate induces autophagy and apoptosis. Sorafenib Tosylate has anti-tumor activity. Sorafenib Tosylate is a ferroptosis activator.

Specifications

Chemical Name or Material Sorafenib Tosylate
CAS 475207-59-1
Color Off-White
Purity Grade Notes Research
Molecular Formula C28H24ClF3N4O6S
Quantity 100 mg
Synonym Bay 43-9006 Tosylate
Solubility Information DMSO : ≥ 31 mg/mL (48.66 mM) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=S(C1=CC=C(C=C1)C)(O)=O.O=C(NC2=CC=C(C(C(F)(F)F)=C2)Cl)NC3=CC=C(OC4=CC(C(NC)=O)=NC=C4)C=C3
Molecular Weight (g/mol) 637.03
Formula Weight 637.03
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
Show More Show Less

Research purposes only

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.