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Sorafenib Tosylate, MedChemExpress

Product Code. p-200096604
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Quantity:
100 mg
500 mg
Unit Size:
100mg
500mg
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Product Code. 16434766

Brand: Medchem Express HY10201A

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Description

MedChemExpress Sorafenib Tosylate (Bay 43-9006 Tosylate) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively.

SorafenibTosylate is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib Tosylate induces autophagy and apoptosis. Sorafenib Tosylate has anti-tumor activity. Sorafenib Tosylate is a ferroptosis activator.

Specifications

Chemical Name or Material Sorafenib Tosylate
CAS 475207-59-1
Color Off-White
Purity Grade Notes Research
Molecular Formula C28H24ClF3N4O6S
Quantity 100 mg
Synonym Bay 43-9006 Tosylate
Solubility Information DMSO : ≥ 31 mg/mL (48.66 mM) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=S(C1=CC=C(C=C1)C)(O)=O.O=C(NC2=CC=C(C(C(F)(F)F)=C2)Cl)NC3=CC=C(OC4=CC(C(NC)=O)=NC=C4)C=C3
Molecular Weight (g/mol) 637.03
Formula Weight 637.03
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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