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Sox17 Mouse anti-Human, Clone: OTI3B10, lyophilized, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies CF500044
This item is not returnable.
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Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
SOX17, also known as transcription factor SOX-17, as the name suggests is a transcription factor or a probable transcriptional activator in the premeiotic germ cells. It belongs to the SRY-related HMG box family of transcription factors with a high-mobility group DNA-binding domain (HMG box), that plays a key role in embryogenesis and binds to the sequences 5′-AACAAT-′3 or 5′-AACAAAG-3′. SOX17 plays an essential role in cardiac mesoderm specification as well as in definitive hematopoiesis, maintaining fetal hematopoietic stem cells, hematopoiesis in the fetal liver and yolk sac. Along with beta-catenin, it is known to cooperate in the regulation of transcription of endodermal genes. Defects in SOX17are known to cause a severe defects in fetal hematopoiesis.Specifications
| Sox17 | |
| Monoclonal | |
| Unconjugated | |
| SOX17 | |
| VUR3 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 64321 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| OTI3B10 | |
| PBS with 8% trehalose and no preservative; pH 7.3 | |
| Q9H6I2 | |
| SOX17 | |
| Human recombit protein fragment corresponding to amino acids 177-414 of human SOX17 produced in E.coli. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
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