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Invitrogen™ SOX17 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA572815

Product Code. 15921475

  • € 514.00 / 0.10mg

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Description

Description

SOX17 Polyclonal Antibody for ELISA, IHC, Western Blot

SOX17 (transcription factor SOX-17) belongs to the SRY-related HMB box family of transcription factors. It acts as a transcription regulator that binds target promoter DNA and bends the DNA. It binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. SOX17 modulates transcriptional regulation via WNT3A and inhibits Wnt signaling. It promotes degradation of activated CTNNB1. SOX17 plays an essential role in the regulation of embryonic development and is required for normal looping of the embryonic hear tube and for normal development of the definitive gut endoderm. Mutations in the gene can result in vesicoureteral reflux.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SOX17
Polyclonal
Unconjugated
SOX17
HMG transcription factor SOX17; HMG-box transcription factor Sox17; Sox17; Sox-17; SRY (sex determining region Y)-box 17; SRY box 17; SRY-box 17; SRY-box containing gene 17; SRY-box transcription factor 17; SRY-related HMG-box transcription factor SOX17; transcription factor SOX-17; transcription factor SOX-17; LOW QUALITY PROTEIN: transcription factor SOX-17; VUR3
Rabbit
Antigen affinity chromatography
RUO
20671, 312936, 64321
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q61473, Q9H6I2
SOX17
SOX17 antibody for a 16 amino acid peptide near the center of human SOX17. The immunogen is within amino acids 240 - 290 of SOX17.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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