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Invitrogen™ Spartalizumab Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA558363
This item is not returnable.
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Description
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Spartalizumab (PDR001) is a humanized IgG4 monoclonal antibody that targets PD-1 with sub-nanomolar affinity to block its interaction with PD-L1/PD-L2, thereby preventing PD-1 mediated inhibitory signals Transduction leads to the activation of T cells.
Specifications
| Spartalizumab Humanized | |
| Recombinant Monoclonal | |
| Unconjugated | |
| NPVPDR001; NVS240118; PDR001 | |
| Protein A | |
| RUO | |
| Human | |
| Antibody | |
| IgG4SP |
| ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance | |
| 1 mg/mL | |
| 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 | |
| Human | |
| 100 μg | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
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