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Description
Immunogen sequence: ENSAKKKLLR GGLAERLNGL QNRERSAISL WRHQCISYQK TLSGRKSGVL TVKILELHEE CAMQVAMCEQ LLGSPATSSS QSVAPR Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.
Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity.
Specifications
Specifications
| Antigen | SPIDR |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.3 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | SPIDR |
| Gene Accession No. | Q14159 |
| Gene Alias | DNA repair-scaffolding protein; k0146; KIAA0146; Scaffolding protein involved in DNA repair; SPIDR |
| Gene Symbols | SPIDR |
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Product Title
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