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SPP1 Mouse anti-Human, Clone: OTI6C12, lyophilized, TrueMAB™

Product Code. 17638761
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Quantity:
100 μg
Unit Size:
100µg
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17638761 100 μg 100µg
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Product Code. 17638761 Supplier Origene Technologies Supplier No. CF806238

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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in maligt glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.

Specifications

Antigen SPP1
Applications Western Blot
Classification Monoclonal
Clone OTI6C12
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene SPP1
Gene Accession No. P10451
Gene Alias BNSP, BSPI, ETA-1, OPN
Gene Symbols SPP1
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 17-314 of human SPP1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6696
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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