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Description
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Specifications
Specifications
| Antigen | SPR |
| Applications | Immunoprecipitation, Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence |
| Classification | Polyclonal |
| Concentration | 0.3 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | SPR |
| Gene Accession No. | P18297, P35270, Q64105 |
| Gene Alias | SDR38C1, Sepiapterin reductase, SPR |
| Gene Symbols | SPR |
| Show More |
Product Title
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