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Invitrogen™ SPRY2 Recombinant Rabbit Monoclonal Antibody (24GB2525)

Product Code. 30275665
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20 μL
100 μL
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30275665 20 μL 20µL
30276401 100 μL 100µL
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Product Code. 30275665 Supplier Invitrogen™ Supplier No. MA557264

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Rabbit Recombinant Monoclonal Antibody

SPRY2 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPRY2
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 24GB2525
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SPRY2
Gene Accession No. O43597
Gene Alias hSPRY2; IGAN3; MGC23039; protein sprouty homolog 2; sprouty 2; sprouty homolog 2; sprouty homolog 2 (Drosophila); sprouty RTK signaling antagonist 2; sprouty2; SPRY2; spry-2
Gene Symbols SPRY2
Host Species Rabbit
Immunogen A synthesized peptide derived from human Sprouty 2 (aa 250-315).
Purification Method Affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10253
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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