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Invitrogen™ SR-BI Monoclonal Antibody (3D12)
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Product Code. 17175273
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Quantity:
100 μg
Unit Size:
100µg
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17175273 100 μg 100µg
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Product Code. 17175273 Supplier Invitrogen™ Supplier No. MA533380

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Description

Mouse Monoclonal Antibody

Product is supplied at 1 mL (100 μL/mL). Application Notes: Functional Assay- This antibody is useful for neutralization of the biological activity of SR-BI. For neutralization of biological activity dilutions have to be made according to the amounts SR-BI to be inactivated.

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
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Specifications

Antigen SR-BI
Applications Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone 3D12
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and no preservative
Gene SCARB1
Gene Accession No. P97943
Gene Alias AI120173; CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen (collagen type I receptor, thrombospondin receptor-like 1); CD36 antigen-like 1; Cd36l1; CD36-related class B scavenger receptor haSR-BI; CLA1; Cla-1; Collagen type I receptor, thrombospondin receptor-like 1; D5Ertd460e; haSR-bI; HDL QTL 1; Hdlq1; HDLQTL6; high density lipoprotein receptor; Hlb398; mSR-BI; Scarb1; scavanger receptor class B type 1; scavenger receptor b1; scavenger receptor class B member 1; scavenger receptor class B type I; scavenger receptor class B type II; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B1; SRB1; SR-B1; SRBI; SR-BI; SR-BII
Gene Symbols SCARB1
Host Species Mouse
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25073
Target Species Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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