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Invitrogen™ SRC1 Monoclonal Antibody (1135/H4)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA1840
This item is not returnable.
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Description
MA1-840 detects steroid receptor coactivator-1 (SRC-1) from mouse and primate tissues and cells as well as recombinant human SRC-1 protein. MA1-840 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot MA1-840 detects an ~165 kDa protein representing SRC-1 in COS cell extract. Also by Western blot, MA1-840 detects an unidentified protein at ~30-40 kDa. This antibody does not react with NIH-3T3 cells in Western blot. The MA1-840 immunogen is a synthetic peptide corresponding to residues 477-947 of human SRC-1. The epitope for MA1-840 has been mapped to the extreme C-terminal end of this fragment.
Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1. SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity. SRC-1 has a molecular weight of 160 kDa and has a basic helix-loop-helix (bHLH)-PAS domain.
Specifications
| SRC1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1 mg/mL BSA and 0.05% sodium azide | |
| P70365, Q15788 | |
| NCOA1 | |
| Synthetic peptide corresponding to residues 477-947 of human SRC-1. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Monkey | |
| Antibody | |
| IgG1 |
| ChIP Assay, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 1135/H4 | |
| Unconjugated | |
| NCOA1 | |
| ASV; bHLHe42; bHLHe74; class E basic helix-loop-helix protein 74; c-SRC; F-SRC-1; Hin-2 protein; KAT13A; mNRC-1; NCOA1; NCoA-1; Nuclear receptor coactivator 1; nuclear receptor coactivator protein 1; p60-Src; PAX3/NCOA1 fusion protein; Protein Hin-2; Renal carcinoma antigen NY-REN-52; RIP160; Src1; SRC-1; SRC-1 (-Q); SRC-a/NCoA-1; Steroid receptor coactivator 1; steroid receptor coactivator-1 | |
| Mouse | |
| Purified | |
| RUO | |
| 17977, 8648 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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