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Invitrogen™ SRY Monoclonal Antibody (1G4)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA517181
This item is not returnable.
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Description
MA5-17181 targets SRY in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17181 immunogen is purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli. MA5-17181 detects SRY which has a predicted molecular weight of approximately 23.9kDa.
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.
Specifications
| SRY | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide | |
| Q05066 | |
| SRY | |
| Purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
| 1G4 | |
| Unconjugated | |
| SRY | |
| essential protein for sex determination in human males; HMG box transcription factor Sry1; HMG box transcription factor Sry3BI; sex determining region of Chr Y; sex determining region on Y; sex determining region Y; sex determining region Y protein; sex-determining region on Y; sex-determining region Y protein; SRXX1; SRXY1; Sry; Sry1; Sry3BI; SRYGENE; TDF; TDY; Testis determining locus; testis determining-Y; testis-determining factor; testis-determining factor on Y | |
| Mouse | |
| Protein G | |
| RUO | |
| 6736 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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