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Invitrogen™ SSEA1 Monoclonal Antibody (MC-480)
Mouse Monoclonal Antibody
Brand: Invitrogen™ 411200
This item is not returnable.
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Description
SSEA1 Monoclonal Antibody for Western Blot, ICC/IF, Flow
CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
Specifications
| SSEA1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.1% sodium azide; pH 7.4 | |
| P22083, Q11127 | |
| FUT4 | |
| X-irradiated F9 teratocarcinoma stem cells. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgM |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| MC-480 | |
| Unconjugated | |
| FUT4 | |
| FUTIV; Lewis X; SSEA-1 | |
| Mouse | |
| Protein A | |
| RUO | |
| 14345, 2526 | |
| -20°C | |
| Liquid |
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