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Invitrogen™ STAR Recombinant Rabbit Monoclonal Antibody (HL1360)

Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA547013
This item is not returnable.
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Description
Store as concentrated solution. Centrifuge briefly prior to opening vial.
Steroidogenic acute regulatory protein (StAR) plays a significant role in cholesterol transport from the cytoplasmic outer membrane to the inner mitochondrial membrane. The 37 kDa precursor is cleaved to generate an active 28 kDa protein capable of facilitating cholesterol metabolism into pregnenolone. StAR is prevalently expressed in mitochondria of steroid-producing adrenal and gonadal tissue. Abnormalities in StAR gene expression are impacted in autosomal Lipoid Congenial Adrenal Hyperplasia (LCAH) resulting in defects in pregnenolone and cortisol synthesis. The mechanism of cholesterol binding to StAR has yet to be elucidated.
Specifications
| STAR | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| P49675, P51557 | |
| STAR | |
| Recombinant protein encompassing a sequence within the center region of human StAR. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| HL1360 | |
| Unconjugated | |
| STAR | |
| AV363654; cholesterol trafficker; D8Ertd419e; lipid transporter; luteinizing hormone-induced protein; mitochondrial steroid acute regulatory protein; STAR; StAR related lipid transfer (START) domain containing 1; stARD1; StAR-related lipid transfer (START) domain containing 1; START domain containing 1; START domain-containing protein 1; steroid acute regulatory protein; steroidogenic acute regulator; steroidogenic acute regulatory protein; steroidogenic acute regulatory protein, mitochondrial; testis secretory sperm-binding protein Li 241mP | |
| Rabbit | |
| Protein A | |
| RUO | |
| 20845, 6770 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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