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Invitrogen™ STAT2 Recombinant Rabbit Monoclonal Antibody (4A5P8)
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Product Code. 17719403
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Quantity:
100 μL
Unit Size:
100µL
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17719403 100 μL 100µL
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Product Code. 17719403 Supplier Invitrogen™ Supplier No. MA542828

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: KLPFWTWLDK ILELVHDHLK DLWNDGRIMG FVSRSQERRL LKKTMSGTFL LRFSESSEGG ITCSWVEHQD DDKVLIYSVQ PYTKEVLQSL PLTEIIRHYQ LLTEENIPEN PLRFLYPRIP RDEAFGCYYQ EKVNLQERRK YLKHRLIVVS NRQVDEL; Positive test controls include: A-549, U-937, Mouse brain, Rat testis. The target is usually found in the following locations: Cytoplasm, Nucleus.

STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STAT2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 4A5P8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Stat2
Gene Accession No. P52630
Gene Alias 1110034C02Rik; 1600010G07Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; Aprf; AW109958; AW496480; DNA-binding protein APRF; EGK_03803; HIES; IMD44; interferon alpha induced transcriptional activator; ISGF-3; MGC59816; p113; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); STAT; STAT 2; STAT113; STAT2; STAT-2; Stat3
Gene Symbols Stat2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 550-706 of human STAT2 (NP_0054101).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 288774, 6773
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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