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Invitrogen™ STAT6 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA517673
This item is not returnable.
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Description
It is not recommended to aliquot this antibody.
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
Specifications
| STAT6 | |
| Polyclonal | |
| 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 | |
| P42226, P52633 | |
| STAT6 | |
| Synthetic peptide corresponding to residues surrounding amino acid 620 of human Stat6. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Bovine | |
| Antibody | |
| IgG |
| Immunoprecipitation, Western Blot | |
| Unconjugated | |
| STAT6 | |
| 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 20852, 353105, 362896, 6778 | |
| -20°C | |
| Liquid |
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