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Invitrogen™ STEAP3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA520406
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Description
A suggested positive control is rat liver tissue lysate. PA5-20406 can be used with blocking peptide PEP-0523.
The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
Specifications
| STEAP3 | |
| Polyclonal | |
| Unconjugated | |
| STEAP3 | |
| 1010001D01Rik; AHMIO2; dudlin 2; dudlin-2; dudulin 2; dudulin-2; hpHyde; hTSAP6; Metalloreductase STEAP3; pHyde; Protein nm1054; six-transmembrane epithelial antigen of prostate 3; STEAP family member 3; STEAP family member 3, metalloreductase; STEAP3; STEAP3 metalloreductase; STMP3; TSAP6; tumor suppressor pHyde; tumor suppressor-activated pathway protein 6 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 170824, 55240, 68428 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q5RKL5, Q658P3, Q8CI59 | |
| STEAP3 | |
| A 15 amino acid peptide from near the amino terminus of human STEAP3. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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