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STIM2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. p-7209471 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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Product Code. Quantity unitSize
16870815 20 μL 20µL
16860815 150 μL 150µL
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Product Code. 16870815 Supplier Proteintech Supplier No. 211921AP20UL

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Description

Rabbit Polyclonal Antibody

In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.

Specifications

Antigen STIM2
Applications Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene STIM2
Gene Accession No. P83093, Q9P246
Gene Alias KIAA1482, STIM2, stromal interaction molecule 2
Gene Symbols STIM2
Host Species Rabbit
Immunogen STIM2 Fusion Protein Ag15530
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116873, 117087, 57620
Target Species Rat, Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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