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STMN4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12027-1-AP-20UL
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Description
RB3 (Stathmin-4), encoded by STMN4 gene, is a neuron-specific homologue of the SCG10/stathmin family proteins, possessing a unique N-terminal membrane-associated domain and the stathmin-like domain at the C terminus, which promotes microtubule (MT) catastrophe and/or tubulin sequestering. Stathmin is a ubiquitous cytosolic phosphoprotein, preferentially expressed in the nervous system, and described as a relay integrating diverse intracellular signaling pathways. RB3 is consistently up-regulated in differentiated neuroblastoma cells, and stable expression of transfected RB3 could induce differentiation, suggesting a role of RB3 during neuroblastoma differentiation. Moreover, increased RB3 is a unique response protein in the stathmin-related proteins following optical nerve axotomy and RB3 may be a critical target for neurodegenerative diseases.Specifications
| STMN4 | |
| Polyclonal | |
| Unconjugated | |
| STMN4 | |
| RB3, Stathmin 4, stathmin like 4, Stathmin like protein B3, STMN4 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 56471, 79423, 81551 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin) | |
| 0.41 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P63042, P63043, Q9H169 | |
| Stmn4 | |
| STMN4 Fusion Protein Ag2657 | |
| 20 μL | |
| Primary | |
| Human, Rat, Mouse | |
| Antibody | |
| IgG |
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