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Invitrogen™ STRAP Monoclonal Antibody (A7H11)
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Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA544959

Product Code. 17868572

  • € 481.00 / 100µL

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Description

Description

STRAP Monoclonal Antibody for Western Blot, IHC (P)

STRAP is a 350 amino acid MAP activator with WD-40 repeats that is localized both in the cytoplasm and the nucleus. It is a ubiquitously expressed protein that acts as an inhibitor of TGF-beta signaling and an important regulator of cell proliferation. Stable expression of STRAP results in activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and in down-regulation of the cyclin-dependent kinase inhibitor p21 (Cip1), which results in retinoblastoma protein hyperphosphorylation. Upregulation of STRAP might play a role in tumor development as an early event for colorectal cancers. It is the first component of the U snRNP assembly machinery that associates with SMN complex in a compartment-specific way and plays a crucial role in the intracellular distribution of SMN1.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

STRAP
Monoclonal
2 mg/mL
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Q9Y3F4
Strap
Recombinant protein within human STRAP aa 201-350/350.
100 μL
Primary
Human
Antibody
IgG1
Immunohistochemistry (Paraffin), Western Blot
A7H11
Unconjugated
Strap
AW557906; C78091; C79202; MAP activator with WD repeats; MAWD; PT-WD; serine/threonine kinase receptor associated protein; Serine-threonine kinase receptor-associated protein; STRAP; UNR-interacting protein; UNRIP; WD-40 repeat protein PT-WD
Mouse
Protein G
RUO
11171
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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