Invitrogen™ Synapsin Pan Polyclonal Antibody

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases SYN1 (Synapsin I) plays a role in regulation of axonogenesis and synaptogenesis The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal SYN2 (Synapsin II) encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal The protein encoded by SYN3 (Synapsin III) shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation The protein contains a unique domain J, located between domains C and E.