missing translation for 'onlineSavingsMsg'
Learn More

Synaptophysin Monoclonal Antibody (EP10), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

€ 133.00 - € 422.00

Specifications

Antigen Synaptophysin
Clone EP10
Concentration 0.5 mg/mL
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15217727
View Documents Promotion Details
Affymetrix eBioscience
14-6525-80
25 μg
€ 133.00
25µg
View alternative products
Save Up to 
»
Estimated Shipment: 08-05-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
15227727
View Documents Promotion Details
Affymetrix eBioscience
14-6525-82
100 μg
€ 422.00
100µg
View alternative products
Save Up to 
»
Estimated Shipment: 08-05-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: This EP10 monoclonal antibody reacts with human Synaptophysin, which is also known as Major Synaptic Vesicle Protein p38. This 38-kDa integral membrane protein is expressed on neuronal presynaptic vesicles in the brain, spinal cord, retina, neuromuscular junctions, and adrenal medulla. Synaptophysin is also expressed in neuroendocrine tumors and neuroblastomas. Synaptophysin has been reported to play a role in synaptic vesicle trafficking. The EP10 antibody recognizes human and hamster synaptophysin but does not recognize mouse and rat synaptophysin. Applications Reported: This EP10 antibody has been reported for use in immunoprecipitation, immunoblotting (WB), immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, and immunocytochemistry (ICC). Applications Tested: This EP10 antibody has been tested by immunohistochemistry on formalin fixed paraffin embedded human cerebellum using citrate buffer antigen retrieval. This antibody can be used at less than or equal to 5 μg/mL. This EP10 antibody has also been tested by western blot on human brain lysate and can be used at less than or equal to 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
Specifications

Specifications

Synaptophysin
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1
Syp
Primary
4° C
Syp
EP10
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
Mouse
Hamster, Human
P08247
100758282, 6855
IgG1 κ
Affinity chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only.