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Invitrogen™ Synip Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA554629
This item is not returnable.
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Description
Immunogen sequence: LLPCDSSEAD EMERLKCERD DALKEVNTLK EKLLESDKQR KQLTEELQNV KQEAKAVVEE TRALHSRIHL A Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 76%.
STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
Specifications
| Synip | |
| Polyclonal | |
| Unconjugated | |
| Stxbp4 | |
| 6030470M02Rik; FLJ16496; MGC149829; MGC50337; STX4-interacting protein; Stxbp4; Synip; syntaxin 4 interacting protein; syntaxin 4-interacting protein; syntaxin binding protein 4; syntaxin-binding protein 4 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 252983 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.6 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q6ZWJ1 | |
| Stxbp4 | |
| Recombinant protein corresponding to Human Synip. Recombinant protein control fragment (Product #RP-93360). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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