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Invitrogen™ SYNPO2L Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA563082
This item is not returnable.
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Description
Immunogen sequence: PAEALLLPHG PLRPGPHLIP MVGPVPHPVA EDLTTTYTQK AKQAKLQRAE SLQEKSIKEA KTKCRTIASL LTA Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 99%.
SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
Specifications
| SYNPO2L | |
| Polyclonal | |
| Unconjugated | |
| SYNPO2L | |
| 1110054M18Rik; Chap; RGD1565434; synaptopodin 2 like; synaptopodin 2-like; synaptopodin 2-like protein; SYNPO2L | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 79933 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9H987 | |
| SYNPO2L | |
| Recombinant protein corresponding to Human SYNPO2L. Recombinant protein control fragment (Product #RP-101447). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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