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Invitrogen™ Synuclein alpha/beta Monoclonal Antibody (Syn 202)

Product Code. 10622764
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100 μg
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10622764 100 μg Each
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Product Code. 10622764 Supplier Invitrogen™ Supplier No. 328200

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Description

Mouse Monoclonal Antibody

Synuclein alpha/beta Monoclonal Antibody for Western Blot, ICC/IF, IHC, IP, ELISA

Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Synuclein alpha/beta
Applications ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone Syn 202
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene Snca
Gene Accession No. O55042, P37377, P37840, Q16143, Q63754, Q91ZZ3
Gene Alias AI838531; alphaSYN; alpha-synuclein; betaSYN; Beta-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Phosphoneuroprotein 14; PNP 14; SNCA; Sncb; Syn; synuclein alpha; synuclein alpha-140; synuclein beta; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor); synuclein, beta
Gene Symbols Snca, SNCB
Host Species Mouse
Immunogen Recombinant human alpha- and beta-synuclein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 104069, 113893, 20617, 29219, 6620, 6622
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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