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Invitrogen™ TAF1A Polyclonal Antibody

Description
Immunogen sequence: HQWQQAAEYM YSYFQTLEDS DSYKRQAAPE IIWKLGSEIL FYHPKSNMES FNTFANRMKN IGVMNYLKIS LQHALYLLHH GMLKDAKRNL SE Highest antigen sequence indentity to the following orthologs: Rat - 84%, Mouse - 87%.
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, also known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
Specifications
Specifications
| Antigen | TAF1A |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.3 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | TAF1A |
| Gene Accession No. | Q15573 |
| Gene Alias | MGC:17061; mTAFI48; RAFI48; RNA polymerase I-specific TBP-associated factor 48 kDa; similar to TBP-associated factor 1A isoform 1; SL1; SL1, 48kD subunit; Taf1a; TAFI48; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa; TATA box binding protein associated factor 1A; TATA box binding protein-associated factor TAF1A; TATA box-binding protein-associated factor 1A; TATA box-binding protein-associated factor RNA polymerase I subunit A; TATA-box binding protein associated factor, RNA polymerase I subunit A; TATA-box binding protein associated factor, RNA polymerase I, A; TBP-associated factor 1A; Transcription factor SL1; transcription initiation factor SL1/TIF-IB subunit A |
| Gene Symbols | TAF1A |
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