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Invitrogen™ Tafolecimab Recombinant Human Monoclonal Antibody
Human Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA542291
This item is not returnable.
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Description
Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
GPRC5D/CD3 bispecific antibody is used to treat multiple myeloma. The bispecific antibody is generically named tafolecimab. It is constructed using the Duobody technology authorized by Genmab. The heavy chain of the anti-CD3 antibody is introduced into F405L and R409K to construct the double antibody. S228P, F234A, and L235A mutations were also introduced into the IgG4 constant region.
Specifications
| Tafolecimab | |
| Recombinant Monoclonal | |
| Unconjugated | |
| IBI-306 | |
| Human PCSK9. | |
| 100 μg | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid | |
| Chemical |
| ELISA, SDS-Page | |
| 1.02 mg/mL | |
| PBS with no preservative; pH 7.4 | |
| Human | |
| Protein A | |
| RUO | |
| Human | |
| Antibody | |
| IgG2 κ |
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